The ESA is investigating hibernation technology that could allow astronauts to remain healthy during long-duration missions to Mars and beyond. A renewed era of space exploration is upon us, and many exciting missions will be headed to space in the coming years. These include crewed missions to the Moon and the creation of permanent bases there. Beyond the Earth-Moon system, there are multiple proposals for crewed missions to Mars and beyond. This presents significant challenges since a one-way transit to Mars can take six to nine months. Even with new propulsion technologies like nuclear rockets, it could still take more than three months to get to Mars. In addition to the physical and mental stresses imposed on the astronauts by the dur